Claisen-Schmidt condensation of 2,4-dihydroxyacetophenone with aromatic aldehydes are carried out efficiently in the presence of magnesium hydrogensulfate under solvent-free conditions in good to excellent yield without the occurrence of any self-condensation. Similar reactions in solution do not proceed satisfactorily. The structures of the synthesized compounds were confirmed by IR, mass spectroscopy and elemental analysis.
Loading....